Lucy de Jong
Molecular Biologist And Bioinformatician
Wellington,New Zealand
Summary
I am a molecular biologist with practical experience in bioinformatics and programming. I have had three years experience in the personalised medicine industry focusing on cancer therapeutics, analysing Next-Gen sequencing data and clinical research data to map tumour molecular profiles to help identify better treatment options. More recently, I have been working on viral alignments of the Sars-CoV-2 genome to identify mutations that might interfere with vaccine development.
I am highly motivated to grow my career around the central dogma of molecular biology.
LinkedIn profile: https://www.linkedin.com/in/lucy-de-jong-5155b41a9/
Overview
4
4
years of professional experience
4
4
years of post-secondary education
Work History
Bioinformatics Engineer
NantHealth
Los Angeles, California, United States
11.2017 - Current
- Developed program for neoepitope design using a genetic algorithm.
- Analysed DNA through to protein mutations and subsequent binding ability of antigens.
- Statistical analysis on differences and similarities between patient groups based on various kinds of data (e.g. genomic and transcriptomic, expression data, treatment plans and prescriptions).
- Classifier development and machine learning for mutational signatures of tumours.
- Analysis of mutational signature differences between WGS and WES.
- Big data analysis on distributed datasets using Pyspark.
Research Assistant
University Of Otago
Christchurch, Christchurch, New Zealand
12.2016 - 05.2017
- Planned and carried out genomic lab tests and data analysis to supplement the paper submission sourced mainly from Honour's research.
- PCR, qPCR, NGS data analysis, data and writing preparation for submission to publications.
Education
Bachelor of Biomedical Sciences With Honours - Molecular Biology
University of Otago
Christchurch, New Zealand 02.2016 - 11.2016
Bachelor of Biomedical Sciences - Molecular Basis of Health And Disease
University of Otago
Dunedin, New Zealand 02.2013 - 11.2015
Skills
Python for Data Science
Bioinformatic tools (eg samtools, multiple sequence alignments)
Statistical, graphing, visual packages and programs
Linux system navigation and simple bash scripting
Big data analysis on distributed systems
Webscraping
Project management
Standard genomic and protein based wet-lab techniques
DNA and RNA extraction
NGS library prep
Publications
- De Jong, L.C., Cree, S., Lattimore, V. et al. Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Res 19, 127 (2017). https://doi.org/10.1186/s13058-017-0919-1
- Walker, L., Lattimore, V., Kvist, A. et al. Comprehensive Assessment of BARD1 Messenger Ribonucleic Acid Splicing With Implications for Variant Classification. Frontiers in Genetics, 10 (2019). https://doi.org/10.3389/fgene.2019.01139
Timeline
Bioinformatics Engineer
NantHealth
11.2017 - Current
Research Assistant
University Of Otago
12.2016 - 05.2017
Bachelor of Biomedical Sciences With Honours - Molecular Biology
University of Otago
02.2016 - 11.2016
Bachelor of Biomedical Sciences - Molecular Basis of Health And Disease
University of Otago
02.2013 - 11.2015