Lucy de Jong
Molecular Biologist And Bioinformatician
Wellington,New Zealand
Summary
I am a molecular biologist with practical experience in bioinformatics and programming. I have had three years experience in the personalised medicine industry focusing on cancer therapeutics, analysing Next-Gen sequencing data and clinical research data to map tumour molecular profiles to help identify better treatment options. More recently, I have been working on viral alignments of the Sars-CoV-2 genome to identify mutations that might interfere with vaccine development.
I am highly motivated to grow my career around the central dogma of molecular biology.
LinkedIn profile: https://www.linkedin.com/in/lucy-de-jong-5155b41a9/
Overview
4
4
years of professional experience
4
4
years of post-secondary education
Work History
Bioinformatics Engineer
NantHealth
Los Angeles, California, United States
11.2017 - Current
- Developed program for neoepitope design using a genetic algorithm.
- Analysed DNA through to protein mutations and subsequent binding ability of antigens.
- Statistical analysis on differences and similarities between patient groups based on various kinds of data (e.g. genomic and transcriptomic, expression data, treatment plans and prescriptions).
- Classifier development and machine learning for mutational signatures of tumours.
- Analysis of mutational signature differences between WGS and WES.
- Big data analysis on distributed datasets using Pyspark.
Research Assistant
University Of Otago
Christchurch, Christchurch, New Zealand
12.2016 - 05.2017
- Planned and carried out genomic lab tests and data analysis to supplement the paper submission sourced mainly from Honour's research.
- PCR, qPCR, NGS data analysis, data and writing preparation for submission to publications.
Education
Bachelor of Biomedical Sciences With Honours - Molecular Biology
University of Otago
Christchurch, New Zealand 02.2016 - 11.2016
Bachelor of Biomedical Sciences - Molecular Basis of Health And Disease
University of Otago
Dunedin, New Zealand 02.2013 - 11.2015
Skills
Python for Data Science
undefinedPublications
- De Jong, L.C., Cree, S., Lattimore, V. et al. Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events. Breast Cancer Res 19, 127 (2017). https://doi.org/10.1186/s13058-017-0919-1
- Walker, L., Lattimore, V., Kvist, A. et al. Comprehensive Assessment of BARD1 Messenger Ribonucleic Acid Splicing With Implications for Variant Classification. Frontiers in Genetics, 10 (2019). https://doi.org/10.3389/fgene.2019.01139
Timeline
Bioinformatics Engineer
NantHealth
11.2017 - Current
Research Assistant
University Of Otago
12.2016 - 05.2017
Bachelor of Biomedical Sciences With Honours - Molecular Biology
University of Otago
02.2016 - 11.2016
Bachelor of Biomedical Sciences - Molecular Basis of Health And Disease
University of Otago
02.2013 - 11.2015
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